Circulating Cell-Free Mitochondrial DNA as Biomarker of Cardiovascular risk: New Challenges of Old Findingsi

Cardiovascular (CV) disease remains a major cause of mortality and morbidity worldwide, a widely spread illness worldwide and associated with increasing mortality within last decades [1]. Therefore, the high burden of CV and metabolic risk factors in different countries may have been affected the increased incidences of death in subjects prior to documentation of CV disease. In this context, it is needed to extend the exploration of novel biological markers that are reflected various faces of pathogenesis of CV and metabolic diseases.